Systems Biology
From HPSIGWiki
Systems Biology has a large scale research agenda for Modeling Cellular Systems and linking cell component structure and interaction networks to overall component and cellular macroscopic dynamics, involving multilevel models of spatial and temporal scales.
- B.P. Tu et al., "Logic of the yeast metabolic cycle: temporal compartmentalization of cellular processes," Science,310:1152-8 ,Nov. 18, 2005. This paper examines oscillation in metabolic and cell-cycle processes.
- O. Brandman et al., "Interlinked fast and slow positive feedback loops drive reliable cell decisions," Science, 310:496-8, Oct. 21, 2005. This paper explores positive feedback loops in various cell types and (it appears) loop dominance.
- Nature Reviews on Molecular Cell Biology March 2006 Web focus on Modelling Cellular Systems http://www.nature.com/nrm/focus/modelling/index.html for a review (accessed March 1.2006)
- Systems Biology Research Group UCSD
- Biomodels Database
- Systems Biology Markup Language
- CellDesigner Software
- MIRIAM Bringing quality control to systems biology modeling (Accessed March 4.2006)
